Asian Institute of Research, Journal Publication, Journal Academics, Education Journal, Asian Institute
Asian Institute of Research, Journal Publication, Journal Academics, Education Journal, Asian Institute

Journal of Health and Medical Sciences

ISSN 2622-7258

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Published: 25 August 2022

Leptomeningeal Schistosomiasis: A Case Report of an Atypical Location of Neuroschistosomiasis Presenting as Adult-Onset Seizure

Mark Timothy T. Cinco, Criscely L. Go

Jose R. Reyes Memorial Medical Center

journal of social and political sciences
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doi

10.31014/aior.1994.05.03.228

Pages: 43-51

Keywords: Schistosomiasis, Neuroschistosomiasis, Leptomeninges, Focal Seizure

Abstract

We report a case of a 19-year-old male, single, right-handed, student, Filipino currently living in Novaliches, Quezon City who consulted for the first time at our institution due to stiffening of extremities with a pertinent travel history from the Island of Samar. Evaluation and diagnostics showed a leptomeningeal enhancement and thereafter, a biopsy was made revealing deposition of schistosoma ova at the leptomenineal area. Schistosomiaisis (also known as Bilharzia or Blood Fluke Disease) is widely distributed in the Philippines affecting 24 provinces in Luzon, Visayas, and Mindanao, with 5 million people at risk and approximately 1 million affected in the year 2003. Cerebral schistomiasis is a severe and neglected complication which occurs in less than 5% of infected individuals. Symptoms are non-specific such as headache, vomiting, confusional states, and focal seizures. Typical neuroimaging findings are expected at the spinal cord, cerebellum, and the subcortical area, however leptomeningeal involvement is rarely reported. We report this case to the medical community to give light on the different presentations of the said disease

References

  1. Olveda, D.U., Li, Y., Olveda, R.M., Lam, A.K., McManus, D.P., Chau, T.N.P., Harn, D.A., Williams, G.M., Gray, D.J. and Ross, A.G.P. (2014). Bilharzia in the Philippines: past, present, and future. International Journal of Infectious Diseases, [online] 18, pp.52–56. doi:10.1016/j.ijid.2013.09.011.

  2. Imai, K., Koibuchi, T., Kumagai, T., Maeda, T., Osada, Y., Ohta, N., Koga, M., Nakamura, H., Miura, T., Iwamoto, A. and Fujii, T. (2011). Cerebral Schistosomiasis Due to Schistosoma haematobium Confirmed by PCR Analysis of Brain Specimen. Journal of Clinical Microbiology, 49(10), pp.3703–3706. doi:10.1128/jcm.01073-11.

  3. El Beltagi, A., Salem, K. and Hanoun, M. (2021). Neuro-schistosomiasis with palm tree contrast enhancement pattern, a report of three cases, and review of literature. BJR|case reports, [online] 7(1), p.20200053. doi:10.1259/bjrcr.20200053.

  4. Wu, L., Wu, M., Tian, D., Chen, S., Liu, B., Chen, Q., Wang, J., Cai, Q., Ji, B., Wang, L., Zhang, S., Ruan, D., Zhu, X. and Guo, Z. (2011). Clinical and Imaging Characteristics of Cerebral Schistosomiasis. Cell Biochemistry and Biophysics, 62(2), pp.289–295. doi:10.1007/s12013-011-9294-1.

  5. George, J., Rose, D., Hazrati, L.-N., Majl, L. and Hodaie, M. (2009). Cerebral schistosomiasis--an unusual presentation of an intracranial mass lesion. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques, [online] 36(2), pp.244–247. doi:10.1017/s0317167100006624.

  6. Amaral, R. and Andrade Filho, A. (2015). The clinical and epidemiological profile of neuroschistosomiasis. Journal of the Neurological Sciences, 357, pp.e109–e110. doi:10.1016/j.jns.2015.08.350.