Journal of Health and Medical Sciences
Published: 30 October 2019
To Evaluate Cerebral Infarction Among Hypertensive Patients on Magnetic Resonance Imaging
Ayesha Abdul Rauf Toor, Anmol Abdul Malik, Zunaira Ghouri, Aliza Nadeem, M. Ahmad Nisar, M. Gulraiz Khan, Hasham Hanjra, Humaira Rauf
The University of Lahore, Pakistan
Download Full-Text Pdf
Keywords: Magnetic Imaging Resonance, Cerebral Infarction, Perfusion Weighted Imaging, Diffusion-Weighted Imaging, Hypertension
Background: cerebral infarction among Hypertensive patients is very common that increases the complications of mortality in later age. This study aimed to rule out cerebral infarction among hypertensive patients on Magnetic resonance imaging. Objective: To Evaluate cerebral infarction among hypertensive patients on MRI. Methods: The study will be conducted in 162 hypertensive patients including both Male and female. To assess Cerebral infarction it will be acquired on MRI Results: we separated the subjects on the basis of their age (40-91 years). We grouped the same subjects on the basis of their sex (77 males, 47.5% & 85 females, 52.5% ) calculating their frequency and percentage respectively. The mean values among the age of patients and the standard deviation in subjects is 67.35±10.937. The Frequency and percentage of patients complaining showed that vertigo ( 11.7%), Diabetes Mellitus (45.1 %), Dementia (4.3%) appeared with Cerebral Infarction. We Produced a table where we separated infarction on the basis of NO infarction (53.7%) Numbers of infarction One (16.7%), Two (2.5%) and Multiple (27.2%) collectively (46.4%) Appeared with cerebral infarction among hypertensive patients. The results indicated that 46.4% appeared with cerebral infarction triggerd by hypertention and that hypertension can be the cause of cerebral infarction and can lead to morbidity and mortility particularly in adults. Conclusions: These results show that hypertension can be the cause of cerebral infarction and can lead to morbidity and mortility particularly in adults. This study incorporates up to the minute data regarding cerebral infarction among hypertensive patients on magnetic resonance imaging it is the modality of choice for imaging cerebral infarction. It provided a trend that needs to be validated with further studies and analysis on a bigger population
- Liu H. Application of multimodal CT examination in acute cerebral infarction. Guoji Naoxueguanbing Zazhi. 2011;19(09):687-93.
- Hurley MC, Soltanolkotabi M, Ansari S. Neuroimaging in acute stroke: choosing the right patient for neurointervention. Techniques in vascular and interventional radiology 2012;15(1):19-32
- Šaňák D, Nosál V, Horák D, Bártková A, Zeleňák K, Herzig R, et al. Impact of diffusion-weighted MRI-measured initial cerebral infarction volume on clinical outcome in acute stroke patients with middle cerebral artery occlusion treated by thrombolysis. Neuroradiology 2006;48(9):632-9.
- Tong D, Yenari M, Albers G, O'brien M, Marks M, Moseley M. Correlation of perfusion-and diffusion-weighted MRI with NIHSS score in acute (< 6.5 hour) ischemic stroke. Neurology 1998;50(4):864-9
- Hand P, Wardlaw J, Rivers C, Armitage P, Bastin M, Lindley R, et al. MR diffusion-weighted imaging and outcome prediction after ischemic stroke. Neurology 2006;66(8):1159-63
- Vermeer SE, Longstreth Jr WT, Koudstaal PJ. Silent brain infarcts: a systematic review. The Lancet Neurology 2007;6(7):611-9.
- Kesavadas C, Fiorelli M, Gupta A, Pantano P, Bozzao L, Kapilamoorthy T. Diffusion weighted magnetic resonance imaging in acute ischemic stroke. Indian Journal of Radiology and Imaging 2003;13(4):433-40.
- Bhagavati S, Choi J. Can Transient Drop in Blood Pressure in High-Risk Hypertensive Patients Cause Small Cerebral Infarcts? ISRN Stroke 2013;2013.
- Hoshide S, Kario K, Mitsuhashi T, Sato Y, Umeda Y, Katsuki T, et al. Different patterns of silent cerebral infarct in patients with coronary artery disease or hypertension. American journal of hypertension 2001;14(6):509-15.
- Calamante F, Yim PJ, Cebral JR. Estimation of bolus dispersion effects in perfusion MRI using image-based computational fluid dynamics. Neuroimage 2003;19(2):341-53
- Decker DA, Perry A, Yachnis AT. Vascular and ischemic disorders. In: Practical Surgical Neuropathology: A Diagnostic Approach: Elsevier; 2018. p. 633-58.
- Guermazi A, Miaux Y, Lafitte F, Zahar JR, Gluckman E. CT and MR imaging of central nervous system effects of therapy in patients treated for hematological malignancies. European radiology 2003;13(6):L202-L14
- Alerhand S, Lay C. Spontaneous intracerebral hemorrhage. Emergency Medicine Clinics. 2017 Nov 1;35(4):825-45.
- Brott TH, Thalinger KA, Hertzberg VI. Hypertension as a risk factor for spontaneous intracerebral hemorrhage. Stroke. 1986 Nov;17(6):1078-83.
- Maeda H, Matsumoto M, Handa N, Hougaku H, Ogawa S, Itoh T, Tsukamoto Y, Kamada T. Reactivity of cerebral blood flow to carbon dioxide in hypertensive patients: evaluation by the transcranial Doppler method. Journal of hypertension. 1994 Feb;12(2):191-7.
- Kittner SJ, Stern BJ, Wozniak M, Buchholz DW, Earley CJ, Feeser BR, Johnson CJ, Macko RF, McCarter RJ, Price TR, Sherwin R. Cerebral infarction in young adults: the Baltimore-Washington cooperative young stroke study. Neurology. 1998 Apr 1;50(4):890-4.
- Hougaku H, Matsumoto M, Kitagawa K, Harada K, Oku N, Itoh T, Maeda H, Handa N, Kamada T. Silent cerebral infarction as a form of hypertensive target organ damage in the brain. Hypertension. 1992 Dec;20(6):816-20.