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Asian Institute of Research, Journal Publication, Journal Academics, Education Journal, Asian Institute
Asian Institute of Research, Journal Publication, Journal Academics, Education Journal, Asian Institute

Journal of Health and Medical Sciences

ISSN 2622-7258

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open access

Published: 09 December 2023

Content and Antimicrobial Potential of Cambodia Flower (Plumeria sp.) Extract

I Nyoman Jirna, I Gede Sudarmanto, I Nyoman Gede Suyasa, Ida Ayu Made Sri Arjani,
Cok Dewi Widhya Hana Sundari, I Nyoman Purna, Nyoman Mastra

Poltekkes Kemenkes Denpasar

journal of social and political sciences
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Pages: 185-191

Keywords: Antimicrobial, Cambodia, Phytochemical, Plumeria, Staphylococcus Aureus


The case of infectious disease is caused by Streptococcus aureus bacteria. The handling of the disease is performed by antibiotics. However, antibiotics can cause drug resistance to the bacteria. Natural ingredients with antimicrobial plant medicine have potential for the safe, and more effective disease handling. Cambodia flowers (Frangipani P. alba) are expected to contain a variety of chemical compounds with antimicrobial potential. This research may also contribute to the development of new drugs or natural supplements for infection control. The aim of this study is to identify quantitatively antibacterial phytochemical contents and qualitatively test the antimicrobial potential of Cambodia flower extract. The research was conducted using a true-experimental design of a posttest-only-control design with intervention in the treatment group and control for external factors that may potentially affect the research. The data were analyzed using the Kruskal-Wallis test. The results show that Cambodia flower extract contains phenols, tannins, flavonoids, and saponins, and the extract contains 5.95% phenols, 4.85% tannins, and 3.51% flavonoids. There is a difference in antimicrobial potency at various concentrations (55%, 70%, 85%, and 100%) of Cambodia flower extract in inhibiting the growth of S. aureus with a significance value of 0.000. In the in-vitro test, antimicrobial potential is found in the resistant group (with inhibition zone diameter ≤15 mm) in accordance with NCCLS standards. In conclusion, Cambodia flower is expected to provide a beneficial alternative solution for the community in preventing skin infections caused by S. aureus bacteria.


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