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Asian Institute of Research, Journal Publication, Journal Academics, Education Journal, Asian Institute
Asian Institute of Research, Journal Publication, Journal Academics, Education Journal, Asian Institute

Journal of Health and Medical Sciences

ISSN 2622-7258

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open access

Published: 22 July 2020

Diagnostic Accuracy of Ultrasound in the Detection of Malignant Focal Solid Breast Lesions Taking Biopsy as a Gold Standard

Lina Khaled Jallad, Syed Amir Gilani, Raham Bacha, Asif Hanif, S. Muhammad Yousaf Farooq

University of Lahore, Pakistan

journal of social and political sciences
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Pages: 302-309

Keywords: Solid Breast Lesion, Breast Cancer, Biopsy, Sonography, Noninvasive Method


Background: Now a day’s breast cancer is one of the most common causes of deaths and the most malignant condition among women. Objective: To determine diagnostic accuracy of ultrasound in detection of malignant focal solid breast lesions taking biopsy as a gold standard. Material and methods: This Cross-sectional analytical study was conducted at the department of radiology and pathology of Life Line Hospital. Duration of the study was 9 months after the aproval of synopsis. Ultrasound system (Toshiba Xario) with linear transducer, frequency ranging 7 to 14 MHZ. All 78 participants were scanned while observing international standards of American institute of ultrasound in medicine (AIUM) guidelines for breast sonography. Results: Total 78 females with solid breast lesions were included in this study, out of them 28 (35.90%) were found in right while 50(64.10%) in left side. The distribution of breast lesions in Upper outer quadrant, Lower outer quadrant, Upper inner quadrant, and Lower inner quadrant were 50 (64.10%), 45 (57.49%), 13 (16.67%), 16 (20.51%) and 4 (51.13%) respectively. Mean of the depth to width D/W ration in malignant was 0.78±0.098 (0.42-0.93), while in benign was 0.52±0.141(0.35-0.85). there was a significant difference between the D/W ratio of benign and malignant solid breast lesion. The specificity, sensitivity, positive predictive value, negative predictive value, and diagnostic accuracy of ultrasound while taking histopathology as gold standard were 94.74%, 95.24%, 98.18%, 86.96%, and 94.87% respectively. Conclusion: Ultrasound can differentiate benign and malignant solid breast lesion to a great extent. With the application of this sonographic criteria in the cases of solid breast lesion before biopsy for histologic examination the number of unwanted biopsies will be reduced to a great extent.


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