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Asian Institute of Research, Journal Publication, Journal Academics, Education Journal, Asian Institute
Asian Institute of Research, Journal Publication, Journal Academics, Education Journal, Asian Institute

Journal of Health and Medical Sciences

ISSN 2622-7258

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open access

Published: 30 November 2023

Effect of PM2.5 Exposure among Children with Asthma: A Systematic Review

Clara Virginia Allun, Dian Andriani Ratna Dewi, Putri Aisya Azhari, Suzandi Imam Pradana, Fitria Nurul Aini, Wahyu Iman Utomo, Rafif Muzakki, Evania Marisa Rumbobiar

The Republic of Indonesia Defense University, Army Central Hospital Gatot Soebroto

journal of social and political sciences
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Pages: 145-153

Keywords: PM2.5, Exposure, Children, Asthma, Respiratory


Introduction: Particulate matter (PM), which encompasses tiny particles (PM2.5) and inhalable coarse particles (PM10), is a significant environmental issue that carries potential health consequences, particularly for children, including those who have asthma. This systematic review aims to examine the association between exposure to PM2.5 and the exacerbation of childhood asthma, focusing on publications published between 2018 and 2023. Methods: A comprehensive PubMed search retrieved 147 records, leading to the selection of 11 articles for full-text assessment. Subsequently, four studies meeting the criteria were included in this review, following a meticulous selection process. These studies were rigorously assessed for methodology, study design, and key findings. Results: The chosen studies' findings indicate a negative correlation between short-term PM2.5 exposure and a range of lung function indicators in children diagnosed with asthma. This suggests that prenatal PM2.5 exposure may have enduring effects on respiratory health. Discussion: Childhood asthma, marked by complex pathophysiology involving chronic inflammation and hyperresponsive airways, is indeed influenced by PM2.5 exposure, underlining a multifaceted challenge for public health. Conclusion: This systematic review underscores the importance of addressing environmental PM2.5 as a critical public health concern, particularly for children with asthma. Although the studies in this analysis offer valuable insights, they also underscore the need for additional research to understand the intricate link between exposure to PM2.5 and the worsening of pediatric asthma.


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