Journal of Health and Medical Sciences
Published: 15 October 2021
Sentul Fruit (Sandoricum koetjape) Peel as Anti-Inflammation for Gingivitis after Scaling
I Nyoman Wirata, A.A. Gede Agung, Ni Wayan Arini, Ni Ketut Nuratni
Poltekkes Kemenkes Denpasar, Bali
Download Full-Text Pdf
Keywords: Sentul Peel, Anti-Inflammation, Gingivitis
Various herbs are used as analgesic, anti-inflammatory, anti-bacterial, anti-fungal, expectorant, anti-plaque and odorant. Sentul is an edible fruit and is also used in traditional medicinal herbs which can treat diarrhea, relieve fever, and as an anthelmintic. Sentul bark methanol extract can inhibit the growth of fungus Candida albican by 39.65%. In addition, the ethyl acetate extract of the sentul leaves also has anti-bacterial activity. The aim of this study is to determine the effect of fractionation with different types of solvents on the phytochemical compounds of Sentul fruit peel in Bali province. This research is an experimental study in a laboratory with qualitative and quantitative analysis models of chemical compounds. This research was carried out from March to August 2021. The research location was carried out in the laboratory of the Faculty of Food Technology, Udayana University. Sample criteria was old Sentul peel, about 30 kilograms. Data was collected based on the results of examinations from the Laboratory of the Faculty of Food Technology, Udayana University which subsequently analyzed qualitatively and descriptively. From several phytochemical compounds, flavonoids, saponins and tannins are aromatic hydroxyl groups that act as antibacterial. Therefore, seen from the highest levels of flavonoids, saponins and tannins, aqua fraction of Sentul ethanol extract is the best treatment with flavanoid levels of 11476.16 mg/100g QE, tannins 88.605 mg/g and saponins 6.862 mg/g.
Abarca-vargas, R., Malacara, C. F. P., & Petricevich, V. L. (2016). Characterization of Chemical Compounds with Antioxidant and Cytotoxic Activities in Bougainvillea x buttiana Holttum and Standl , ( var . Rose ) Extracts. Antioxidants, 5(45), 1–11. https://doi.org/10.3390/antiox5040045
Agustiningsih, Wildan, A., & Mindaningsih. (2010). Optimasi Cairan Penyari pada Pembuatan Ekstrak Daun Pandan Wangi (Pandanus amaryllifous Roxb) secara Maserasi Terhadap Kadar Fenolik dan Flavonoid Total. Momentum, 6(2), 36–41.
Aini, R., & Mardiyaningsih, A. (2016). Pandan leaves extract (Pandanus amaryllifolius Roxb) as a food preservative. Indonesian Journal of Medicine and Health, 7(4), 166–173. https://doi.org/10.20885/JKKI.Vol7.Iss4.art8
Aria, W. U., Efdi, M., & Santoni, A. (2013). Isolasi Senyawa Triterpenoid Dari Fraksi Aktif Kulit Batang Kecapi (Sandoricum Koetjape Merr) dan Uji Bioaktifitas “Brineshrimps Lethality Bioassay.” Jurnal Kimia Unand, 2(1).
Diansari, E., Suwarsono, E., & Dalimunthe, A. (2018). Anti diarrhea effect of ethanol extract kecapi bark (Sandoricum Koetjape Merr) on male Guinea pig induced with castor oil and bacteria Escherichia coli. Asian Journal of Pharmaceutical and Clinical Research, 11(13). https://doi.org/10.22159/ajpcr.2018.v11s1.26571
Ferreira, O., & Pinho, S. P. (2012). Solubility of Flavonoids in Pure Solvents. Industrial & Engineering Chemistry Research, 51(18), 6586–6590. https://doi.org/10.1021/ie300211e
Gan, J., Feng, Y., He, Z., Li, X., & Zhang, H. (2017). Correlations between Antioxidant Activity and Alkaloids and Phenols of Maca ( Lepidium meyenii ). Journal of Food Quality, 2017, 1–11. https://doi.org/10.1155/2017/3185945
Grover, V., Mahendra, J., Gopalakrishnan, D., & Jain, A. (2021). Effect of octenidine mouthwash on plaque , gingivitis , and oral microbial growth : A systematic review. Clin Exp Dent Res., 7(July 2020), 450–464. https://doi.org/10.1002/cre2.386
Heliawati, L., Ardianto, D., & Ndruru, S. T. C. L. (2017). Introducing Phytochemical Testing of Sandoricum koetjape Merr. Through Inquiry-Based Learning. In 2nd Asian Education Symposium.
Hodge, P. (2016). Mouthwashes : Do They Work and Should We Use Them ? Part 1 : Antiplaque Efficacy of Mouthwashes. Dental Update, 43(6), 536–544. https://doi.org/10.12968/denu.2016.43.6.536
Juan Moreno, R. P. (2012). Chapter 6 - Sugars: Structure and Classification. In Enological Chemistry (pp. 77–93). Academic Press. https://doi.org/10.1016/B978-0-12-388438-1.00006-6
Karimi, A., Majlesi, M., & Rafieian-kopaei, M. (2015). Herbal versus synthetic drugs; beliefs and facts. J Nephropharmacol, 4(1), 27–30.
Minatel, I. O., Borges, C. V., Ferreira, M. I., Gomez, H. A. G., Chen, C.-Y. O., & Lima, G. P. P. (2017). Phenolic Compounds: Functional Properties, Impact of Processing and Bioavailability. IntechOpen, 1–25. https://doi.org/10.5772/66368
Moein, N., Alavi, F. N., Salari, A., Mojtahedi, A., & Tajer, A. (2020). Effect of Listerine Mouthwash with Green Tea on the Inhibition of Streptococcus Mutans : A Microbiologic Study. Pesquisa Brasileira Em Odontopediatria e Clínica Integrada, 20, 1–6. https://doi.org/10.1590/pboci.2020.106
Murakami, S., Mealey, B. L., Mariotti, A., & Chapple, I. L. C. (2018). Dental plaque – induced gingival conditions. Journal of Periodontology, 89(February 2017), 17–27. https://doi.org/10.1002/JPER.17-0095
Petruczynik, A. (2012). Analysis of alkaloids from different chemical groups by different liquid chromatography methods. Cent. Eur. J. Chem., 10(3), 802–835. https://doi.org/10.2478/s11532-012-0037-y
Prasanth, M. (2011). Antimicrobial Efficacy of Different Toothpastes and Mouthrinses : An In Vitro Study. Dental Research Journal, 8(2), 85–94.
Robinson, T. (1995). Kandungan Organik Tumbuhan Tinggi(VI). Bandung: Kosasih Padmawinata, ITB.
Supriyanto, B.W., S., M, R., & Yunianta. (2017). Uji Fitokimia dan Aktivitas Antioksidan Ekstrak Daun Mimba (Azaradiracta indica Juss). In SNATIF (pp. 523–529).
Tanjaya, J., & Auerkari, E. I. (2011). IL-1 β Genetic Polimorphism in Menopause Women as Periodontal Disease Risk Factor. Journal of Dentistry Indonesia, 18(1), 1–5.
Toobpeng, N., Powthong, P., & Suntornthiticharoen, P. (2017). Evaluation of Antioxidant and Antibacterial Activities of Fresh and Freeze-Dried Selected Fruit Juices. Asian Journal of Pharmaceutical and Clinical Research, 10(9), 156–160. https://doi.org/10.22159/ajpcr.2017.v10i9.19099
Warsinah, Kusumawati, E., & Sunarto. (2011). Identification of Compound Antifungi of Sandoricum koetjape stem and Activity to Candida albicans. Majalah Obat Tradisional, 16(3), 170–178.
Widyawati, P. S., Budianta, T. D. W., Kusuma, F. A., & Wijaya, E. L. (2014). Difference of Solvent Polarity To Phytochemical Content and Antioxidant Activity of Pluchea indicia Less Leaves Extracts. International Journal of Pharmacognosy and Phytochemical Research, 6(4), 850–855.
Yuliana, P., Laconi, E. B., Wina, E., & Jayanegara, A. (2014). Extraction of Tannins and Saponins from Plant Sources and Their Effects on In vitro Methanogenesis and Rumen Fermentation. J. Indonesian Trop. Anim. Agric., 39(June), 91–97.
Yusnawan, E. (2013). The Effectiveness of Polar and Non Polar Fractions of Ageratum Conyzoides L. to Control Peanut Rust Disease and Phytochemical Screenings of Secondary Metabolites. J. HPT Tropika, 13(2), 159–166.
Zhang, Q. W., Lin, L. G., & Ye, W. C. (2018). Techniques for extraction and isolation of natural products : a comprehensive review. Chinese Medicine, 13(20), 1–26. https://doi.org/10.1186/s13020-018-0177-x