Ahmad Mahmood, Mohammad Shoaib, Mustafa Zhayier, Rexiati Ruze, Tiemin Jiang
Xinjiang Medical University, China
Portal hypertension refers to a range of complications that arise from elevated pressure in the portal vein system, which can be caused by various factors. The primary causes of portal hypertension are cirrhosis induced by viral hepatitis and non-cirrhotic factors such as Budd-Chiari syndrome, portal cavernous transformation, and regional portal hypertension. Patients with portal hypertension experience increased blood flow and resistance in the portal vein, leading to enlargement of the spleen and increased splenic function. This, in turn, can result in a decrease in blood cells and an overgrowth of bone marrow hematopoietic cells, leading to complications like anemia, bleeding, and infection. The treatment for splenomegaly induced by portal hypertension involves both medical and surgical approaches, with surgical treatment being the primary method. This article provides an overview of the common treatment options for splenomegaly caused by portal hypertension.